a randomized, controlled trial of levonorgestrel vs. the yuzpe regimen as emergency contraception method among iranian women.
نویسندگان
چکیده
we aimed to compare acceptability of levonorgestrel with the yuzpe regimen among iranian women based on their side-effects and resulting changes in the amount and pattern of menses.five hundred twenty nine participants aged 15-49 having regular menses and one act of unprotected intercourse within 72 h were included in the double-blind, controlled trial in 2006-2007 and randomly assigned into lng (n=263) and hd (n=266) groups, receiving levonorgestrel 0.75 mg given 12 h apart and ethinyl estradiol 100 μg plus 0.5 mg levonorgestrel 0.5 mg repeated after 12 h, respectively.the participants receiving levonorgestrel experienced significantly lower side-effects in the case of nausea, vomiting, and dizziness (p 0.05). no significant difference was observed between the efficiencies of the treatments.significantly lower side-effects of levonorgestrel can be considered as greater acceptability and translated to higher efficiency.
منابع مشابه
A Randomized, Controlled Trial of Levonorgestrel Vs. The Yuzpe Regimen as Emergency Contraception Method among Iranian Women
BACKGROUND We aimed to compare acceptability of Levonorgestrel with the Yuzpe regimen among Iranian women based on their side-effects and resulting changes in the amount and pattern of menses. METHODS Five hundred twenty nine participants aged 15-49 having regular menses and one act of unprotected intercourse within 72 h were included in the double-blind, controlled trial in 2006-2007 and ran...
متن کاملUpdated estimates of the effectiveness of the Yuzpe regimen of emergency contraception.
The purpose of this study was to provide revised estimates of the effectiveness of the Yuzpe method of emergency contraception. Through a literature search, we identified eight studies that present the number of women treated and outcome of treatment by cycle day of unprotected intercourse relative to expected day of ovulation. Using five sets of external estimates of conception probabilities b...
متن کاملProgesterone receptor modulator for emergency contraception: a randomized controlled trial.
OBJECTIVE Compare the efficacy and adverse effects of CDB-2914, a new progesterone receptor modulator, to levonorgestrel for emergency contraception. METHODS We performed a randomized, double-blinded noninferiority trial, enrolling healthy women seeking emergency contraception within 72 hours of unprotected intercourse. Participants were randomly assigned to receive a single dose of 50 mg of ...
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متن کاملMifepristone was more effective than the Yuzpe regimen for emergency contraception.
Patients 1000 women between 16 and 45 years of age seeking emergency contraception within 72 hours after an episode of unprotected sexual intercourse who had regular menstrual cycles (21–35 d), were certain about the dates of their last menstrual period, and were willing to abstain from further acts of unprotected intercourse during the menstrual cycle. Exclusion criteria were use of oral contr...
متن کاملEmergency contraception.
Emergency contraception is used to prevent pregnancy after a coital act not adequately protected by a regular method of contraception. In contrast to early medical abortion, emergency contraception prevents a pregnancy from starting and does not disrupt an established pregnancy. The most commonly used approaches consist of two oral doses of contraceptive steroids. The levonorgestrel-only regime...
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عنوان ژورنال:
iranian journal of public healthجلد ۴۲، شماره ۱۰، صفحات ۱۱۵۸-۱۱۶۶
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